종합병원 종사자에서 분리한 MRSA 및 MSSA의 항균제 내성 및 장독소 양상
Enterotoxin and Antibiotic Resistance Patterns of MRSA and MSSA Isolated from Personnel of General Hospital
김연선, 이정림, 박석기, 이영기,
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김연선 ( Kim Yeon-Sun ) - 단국대학교 일반대학원 보건학과
이정림 ( Lee Jung-Rim ) - 단국대학교 일반대학원 보건학과
박석기 ( Park Seog-Kee ) - 단국대학교 일반대학원 보건학과
이영기 ( Lee Young-Ki ) - 단국대학교 일반대학원 보건학과
KMID : 0829220110350040223
Abstract
This study was carried out to investigate antibiotic resistances of 181 isolates in Staphylococcus aureus isolated from 450 specimens which were a General Hospital personnel in Cheonan province. Of the 181 isolates, 89 isolates (49.2%) were methicillin resistant and 92 isolates were susceptible. They were resistant to penicillin (80.1%), clindamycin (18.8%), oxacillin (49.2%), cefepime (28.2%), cefotetan (34.3%), ampicillin (66.3%), gentamicin (27.6%), tetracycline (17.7%) and erythromycine (43.1%), also. In resistant rates of the 89 MRSA, 5 antibiotics were more than 50%, but in those of the 92 MSSA, only 1 antibiotics was. Also they showed very highly multi-drug resistance patterns to 15 antibiotics as follow : One hundred and forty five isolates(82.3%) showed antibiotic resistance to more than one kind of the 15 kinds antibiotics. In the multiple resistant patterns, one drug resistant isolates were 18 isolates (9.9%), 2 drugs 29 (16.0%), 3 drugs 21 (11.6%), 4 drugs 29 (16.0%), and more than 5 drugs were 52 isolates (28.7%). The number of more than 5 drugs resistant strains in MSSA were only 1 strain, but those in MRSA were 51 isolates (57.3%). Forty five isolates (24.9%) produced enterotoxin serotype C and all MRSA.
키워드
Antibiotics resistance; Enterotoxin; General hospital personnel; MRSA; MSSA
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